Lipo-B Injection

The Lipo-B injection is a product that contains a combination of compounds that have been shown to exhibit lipotropic effects. The lipotropic effects facilitate the burning of adipose tissue within the human body which may, consequently, result in some degree of weight loss. Lipo-B injections are typically used as fat loss supplements, in combination with diet and exercise, in weight loss plans. The combination of products that make up the Lipo-B injection are methionine, choline, and cyanocobalamin (vitamin B12).

Methionine

Methionine is one of the four sulfur-containing amino acids; the other three are cysteine, homocysteine, and taurine. Additionally, it is one of the nine essential amino acids in the human body. As an essential amino acid, it cannot be synthesized de novo by the human body due to a lack of the require metabolic pathway needed for its synthesis. Therefore, methionine has to be exogenously introduced into the human body either within the diet or as a supplement.Lopez, M.J., Mohiuddin, S.S, “Biochemistry, Essential Amino acids”, StatPearls. April 2020. Available: https://www.ncbi.nlm.nih.gov/books/NBK557845/Parkhitko, A.A., Jouandin, P., Mohr, S.E., Perrimon, N.,” Methionine metabolism and methyltransferases in the regulation of aging and lifespan extension across species”, Aging Cell, vol.18 issue 6. December 2019. Available: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826121/

Methionine serves several key roles in the human body such as:

• • Substrate in the production of critical hormones and proteins including L-cysteine, carnitine, adrenaline, choline, and melatonin, among others.

• • Increasing liver production of lecithin which helps lower serum cholesterol levels.

• • Provides sulfur which aids development of nails and promotes hair growth.

• • Chelating agent which helps get rid of heavy metals such as mercury.

• • Provides protection against hepatotoxins such as acetaminophen.“What is methionine?”, amino acid studies. Available: https://aminoacidstudies.org/l-methionine/“Methionine”, Drug Bank. Available: https://go.drugbank.com/drugs/DB00134

Choline

Choline is an essential nutrient that plays a key role in a number of metabolic pathways in the human body. Even though choline is produced endogenously in the liver, it is still considered an essential nutrient because the quantities produced is not sufficient to meet the body’s metabolic needs; as such, dietary supplementation of choline is necessary. Choline can be found in both animal and plant food sources, with animal food sources generally having more choline per gram of food product.

Some functions that choline serves in the body are:

• • Production of sphingomyelin and phosphatidylcholine, which are needed to maintain cell membrane integrity.

• • Production of acetylcholine, which is one of the major neurotransmitters in the body.

• • Modulation of gene expression and cell membrane signaling.

• • Early brain development in fetuses.Korsmo, H.W., “Choline: Exploring the Growing Science on its Benefits for Moms and Babies”, Nutrients, vol.11 issue 8. August 2019. Available: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722688/#:~:text=The%20choline%20adequate%20intake%20(AI,day%20during%20lactation%20%5B3%5D.“Choline”, Fact Sheet for Health Professionals. Available: https://ods.od.nih.gov/factsheets/Choline-HealthProfessional/#h8

Cyanocobalamin

Otherwise known as vitamin B12, cyanocobalamin derives its name from the fact that it has a cyanide group attached to its molecule and also contains the mineral cobalt. It is essential for cellular energy production as well as DNA synthesis. It is an essential water-soluble vitamin and must be obtained from food or as dietary supplements. Some good food sources of vitamin B12 are meat, fish, milk, eggs, and cheese, among others. Some of the roles that cyanocobalamin serves in the body include:

• • Cofactor for methionine synthase and L-methymalonyl-CoA mutase.

• • Synthesis of methionine from homocysteine.

• • Regeneration of tetrahydrofolate from 5-methyltetrahydrofolate.Vasavada, A., Sanghavi, D., “Cyanocobalamin”, StatPearl. Available: https://www.ncbi.nlm.nih.gov/books/NBK555964/#:~:text=Mechanism%20of%20Action&text=Tissues%20absorb%20vitamin%20B12%20by,particularly%20in%20erythroid%20progenitor%20cells.“Vitamin B12 Fact Sheet for Health Professionals”, National Institutes of Health. Available: https://ods.od.nih.gov/factsheets/VitaminB12-HealthProfessional/